Apolipoprotein E, low-density lipoprotein receptor, and immune cells control blood-brain barrier penetration by AAV-PHP.eB in mice
Variants of the adeno-associated virus serotype 9 with enhanced penetration of the blood–brain barrier in rodents and primates | Nature Biomedical Engineering
Blood-brain barrier (BBB) in the context of CNS-targetting... | Download Scientific Diagram
Research – Gradinaru Lab
Frontiers | A Multifaceted Approach to Optimizing AAV Delivery to the Brain for the Treatment of Neurodegenerative Diseases
Selection of rAAV vectors that cross the human blood-brain barrier and target the central nervous system using a transwell model: Molecular Therapy - Methods & Clinical Development
Gene therapy researchers find viral barcode to cross the blood-brain barrier | Newsroom
Endothelium-Macrophage Crosstalk Mediates Blood-Brain Barrier Dysfunction in Hypertension | Hypertension
Engineered AAV Vectors Cross Blood-Brain Barrier in Monkeys
Crossing the blood-brain barrier
Delivering Genes Across the Blood-Brain Barrier | www.caltech.edu
Press Release August 24 2020 - STEM BIOMEDICAL
Crossing the blood-brain barrier with AAV vectors | SpringerLink
AAV9-Retro mediates efficient transduction with axon terminal absorption and blood–brain barrier transportation | Molecular Brain | Full Text
A brain microvasculature endothelial cell‐specific viral vector with the potential to treat neurovascular and neurological diseases | EMBO Molecular Medicine
An adeno-associated virus vector penetrates the blood–brain barrier in non-human primates | Nature Biomedical Engineering
A novel strategy for delivering Niemann‐Pick type C2 proteins across the blood–brain barrier using the brain endothelial‐specific AAV‐BR1 virus - Rasmussen - 2023 - Journal of Neurochemistry - Wiley Online Library
Challenges in adeno-associated virus-based treatment of central nervous system diseases through systemic injection - ScienceDirect
Delivering genes across the blood-brain barrier: LY6A, a novel cellular receptor for AAV-PHP.B capsids | PLOS ONE
Crossing the blood-brain barrier with AAV vectors | SpringerLink
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AAV-PHP.B Administration Results in a Differential Pattern of CNS Biodistribution in Non-human Primates Compared with Mice | ASGCT - American Society of Gene & Cell Therapy
The human brain endothelial barrier: transcytosis of AAV9, transduction by AAV2 - Weber‐Adrian - 2017 - Journal of Neurochemistry - Wiley Online Library
The human brain endothelial barrier: transcytosis of AAV9, transduction by AAV2
Development of Novel Therapeutics Targeting the Blood–Brain Barrier: From Barrier to Carrier in Advanced Science-河南大学国际合作与交流处暨港澳台事务办公室
