![Precise CAG repeat contraction in a Huntington's Disease mouse model is enabled by gene editing with SpCas9-NG | Communications Biology Precise CAG repeat contraction in a Huntington's Disease mouse model is enabled by gene editing with SpCas9-NG | Communications Biology](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs42003-021-02304-w/MediaObjects/42003_2021_2304_Fig1_HTML.png)
Precise CAG repeat contraction in a Huntington's Disease mouse model is enabled by gene editing with SpCas9-NG | Communications Biology
![New molecule can reverse the Huntington's disease mutation in lab models - HDBuzz - Huntington's disease research news. New molecule can reverse the Huntington's disease mutation in lab models - HDBuzz - Huntington's disease research news.](https://en.hdbuzz.net/system/production/media/picture/692/redesignarticle_codev-2020-03-09-a9d916d6b5-7096373457_d3021bfa70_b.jpg)
New molecule can reverse the Huntington's disease mutation in lab models - HDBuzz - Huntington's disease research news.
![Small Molecule Modulates Hairpin Structures in CAG Trinucleotide Repeats - Hagihara - 2011 - ChemBioChem - Wiley Online Library Small Molecule Modulates Hairpin Structures in CAG Trinucleotide Repeats - Hagihara - 2011 - ChemBioChem - Wiley Online Library](https://chemistry-europe.onlinelibrary.wiley.com/cms/asset/c3eebf81-aa4e-4149-9353-d54a7c4aef4d/mcontent.jpg)
Small Molecule Modulates Hairpin Structures in CAG Trinucleotide Repeats - Hagihara - 2011 - ChemBioChem - Wiley Online Library
![Frequency of the loss of CAA interruption in the HTT CAG tract and implications for Huntington disease in the reduced penetrance range | Genetics in Medicine Frequency of the loss of CAA interruption in the HTT CAG tract and implications for Huntington disease in the reduced penetrance range | Genetics in Medicine](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41436-020-0917-z/MediaObjects/41436_2020_917_Fig1_HTML.png)
Frequency of the loss of CAA interruption in the HTT CAG tract and implications for Huntington disease in the reduced penetrance range | Genetics in Medicine
![A) Alignment of sequences flanking and including the site of the CAG... | Download Scientific Diagram A) Alignment of sequences flanking and including the site of the CAG... | Download Scientific Diagram](https://www.researchgate.net/publication/12566354/figure/fig1/AS:340760495968271@1458255041253/A-Alignment-of-sequences-flanking-and-including-the-site-of-the-CAG-repeat-from-the.png)
A) Alignment of sequences flanking and including the site of the CAG... | Download Scientific Diagram
![Approaches to Sequence the HTT CAG Repeat Expansion and Quantify Repeat Length Variation - IOS Press Approaches to Sequence the HTT CAG Repeat Expansion and Quantify Repeat Length Variation - IOS Press](https://content.iospress.com/media/jhd/2021/10-1/jhd-10-1-jhd200433/jhd-10-jhd200433-g002.jpg)
Approaches to Sequence the HTT CAG Repeat Expansion and Quantify Repeat Length Variation - IOS Press
![A) Chromatogram illustrating forward and reverse sequencing of the AR... | Download Scientific Diagram A) Chromatogram illustrating forward and reverse sequencing of the AR... | Download Scientific Diagram](https://www.researchgate.net/publication/256664752/figure/fig1/AS:214294802243584@1428103270228/A-Chromatogram-illustrating-forward-and-reverse-sequencing-of-the-AR-CAG-repeat.png)
A) Chromatogram illustrating forward and reverse sequencing of the AR... | Download Scientific Diagram
![Impact of repeat tract length, location and sequence surrounding the... | Download Scientific Diagram Impact of repeat tract length, location and sequence surrounding the... | Download Scientific Diagram](https://www.researchgate.net/publication/343119421/figure/fig2/AS:916044495470594@1595413435852/mpact-of-repeat-tract-length-location-and-sequence-surrounding-the-targeted-region-on.png)
Impact of repeat tract length, location and sequence surrounding the... | Download Scientific Diagram
![Interrupting sequence variants and age of onset in Huntington's disease: clinical implications and emerging therapies - The Lancet Neurology Interrupting sequence variants and age of onset in Huntington's disease: clinical implications and emerging therapies - The Lancet Neurology](https://www.thelancet.com/cms/asset/d7a56219-1133-41be-95fc-113bfeeff9b3/gr1.jpg)
Interrupting sequence variants and age of onset in Huntington's disease: clinical implications and emerging therapies - The Lancet Neurology
![Uninterrupted CAG repeat drives striatum-selective transcriptionopathy and nuclear pathogenesis in human Huntingtin BAC mice - ScienceDirect Uninterrupted CAG repeat drives striatum-selective transcriptionopathy and nuclear pathogenesis in human Huntingtin BAC mice - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S089662732200006X-fx1.jpg)
Uninterrupted CAG repeat drives striatum-selective transcriptionopathy and nuclear pathogenesis in human Huntingtin BAC mice - ScienceDirect
![Frontiers | Structural Characteristics of Simple RNA Repeats Associated with Disease and their Deleterious Protein Interactions Frontiers | Structural Characteristics of Simple RNA Repeats Associated with Disease and their Deleterious Protein Interactions](https://www.frontiersin.org/files/Articles/256811/fncel-11-00097-HTML/image_m/fncel-11-00097-g001.jpg)
Frontiers | Structural Characteristics of Simple RNA Repeats Associated with Disease and their Deleterious Protein Interactions
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A genetic association study of glutamine-encoding DNA sequence structures, somatic CAG expansion, and DNA repair gene variants, with Huntington disease clinical outcomes - eBioMedicine
![Repeat-associated non-AUG translation induces cytoplasmic aggregation of CAG repeat-containing RNAs | PNAS Repeat-associated non-AUG translation induces cytoplasmic aggregation of CAG repeat-containing RNAs | PNAS](https://www.pnas.org/cms/10.1073/pnas.2215071120/asset/21537a9f-b3bc-4860-8259-1f1c00cf3eec/assets/images/large/pnas.2215071120fig01.jpg)
Repeat-associated non-AUG translation induces cytoplasmic aggregation of CAG repeat-containing RNAs | PNAS
![Translation of HTT mRNA with expanded CAG repeats is regulated by the MID1–PP2A protein complex | Nature Communications Translation of HTT mRNA with expanded CAG repeats is regulated by the MID1–PP2A protein complex | Nature Communications](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fncomms2514/MediaObjects/41467_2013_Article_BFncomms2514_Fig1_HTML.jpg)
Translation of HTT mRNA with expanded CAG repeats is regulated by the MID1–PP2A protein complex | Nature Communications
![Representative gene sequencing of the CAG repeats in androgen receptor... | Download Scientific Diagram Representative gene sequencing of the CAG repeats in androgen receptor... | Download Scientific Diagram](https://www.researchgate.net/publication/233336116/figure/fig1/AS:299965281783812@1448528704669/Representative-gene-sequencing-of-the-CAG-repeats-in-androgen-receptor-exon-1-of-patient.png)
Representative gene sequencing of the CAG repeats in androgen receptor... | Download Scientific Diagram
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